
Dr. Tahereh Forooghifar is a highly skilled gynecologist and female cosmetic surgeon, specializing in: ✔ Pelvic floor reconstruction & urogynecology ✔ Vaginal cosmetic & […]
Preimplantation Genetic Screening is a sophisticated genetic testing procedure performed during in vitro fertilization (IVF) that allows for:
Comprehensive chromosomal analysis of embryos
Detection of genetic abnormalities
Embryo sex determination
Selection of the healthiest embryos for transfer
Screening for chromosomal abnormalities (aneuploidy screening)
Identification of specific genetic disorders
Family balancing through sex selection
Improving IVF success rates
Embryo Biopsy: Removal of 5-10 cells from the trophectoderm (day 5-6 blastocyst)
Genetic Analysis:
Chromosomal screening (24-chromosome analysis)
Specific gene mutation testing (when indicated)
Embryo Selection:
Identification of genetically normal embryos
Optional gender selection
Embryo Transfer: Implantation of selected embryos
✓ Couples with family history of genetic disorders
✓ Women of advanced maternal age (35+)
✓ Couples with recurrent pregnancy loss
✓ Those with previous IVF failures
✓ Families seeking gender balance
Next-generation sequencing (NGS) technology
99% accuracy in chromosomal analysis
Reduced risk of genetic disorders
Increased implantation rates (up to 70% improvement)
Lower miscarriage rates
Gender selection regulations vary by country
Counselling required for informed decision-making
Storage and disposition of unused embryos
Limitations in detecting all genetic conditions
Significantly higher live birth rates per transfer
Reduced time to successful pregnancy
Lower risk of chromosomal conditions (e.g., Down syndrome)
Ability to screen for single gene disorders (when combined with PGD)
While PGS screens for chromosomal abnormalities, Preimplantation Genetic Diagnosis (PGD) tests for specific genetic diseases. Many clinics now combine these approaches for comprehensive genetic assessment.
Expanded carrier screening
Whole genome sequencing
Non-invasive embryo testing development
Improved aneuploidy prediction models
Dr. Tahereh Forooghifar is a highly skilled gynecologist and female cosmetic surgeon, specializing in: ✔ Pelvic floor reconstruction & urogynecology ✔ Vaginal cosmetic & […]
Dr. Fatemeh Bakhtiari Ghale is a renowned obstetrician and gynecologist based in Tehran, specializing in infertility, laparoscopy, and IVF treatments. […]