Key Advantage: Orthokine specifically targets IL-1 inflammation (main driver of OA pain)
Treatment Protocol
Standard Course
3-6 injections (1-2 weeks apart)
Local anesthesia applied
Post-injection Care:
✓ Avoid strenuous activity x 48h
✓ Ice as needed
When to Expect Results
Initial relief: 2-4 weeks
Peak effect: 8-12 weeks
Maintenance: Annual boosters recommended
Ideal Candidates
✔ Patients with mild-moderate arthritis
✔ Those avoiding surgery
✔ Athletes with sports injuries
✔ Individuals intolerant to steroids
Not Recommended For:
✗ Advanced joint destruction
✗ Active infections
✗ Blood clotting disorders
Safety Profile
No allergic reactions (autologous treatment)
Rare temporary swelling/stiffness
FDA-cleared processing systems
Cost & Availability
Price Range: $800-$1,500 per injection (varies by joint)
Insurance: Rarely covered (considered experimental in US)
Global Centers: Widely available in Europe, Middle East
Patient FAQs
Q: How does Orthokine compare to stem cells?
A: Orthokine focuses on inflammation control, while stem cells aim to rebuild tissue. Often used together.
Q: Is there age limit for treatment?
A: Effective for adults of all ages if joints have remaining cartilage.
Q: Can it delay joint replacement?
A: Yes, by 2-5 years in suitable candidates.
Dr. Mahnaz Narimani ZamanAbadi is a leading pain medicine specialist and anesthesiologist in Tehran, combining over 25 years of clinical expertise with academic […]
Dr. Mohammad Ali Hatamian is a renowned orthopedic surgeon in Tehran, Iran, with 23+ years of experience in bone, joint, and trauma surgery. Recognized by the Iranian […]
