

Dr. Leila Majdi is a highly experienced obstetrician-gynecologist and infertility specialist based in Urmia, Iran, providing compassionate and personalized care […]
Polycystic Ovary Syndrome (PCOS) is one of the most common hormonal endocrine disorders among women of reproductive age, affecting an estimated 1 in 10 women. While its name refers to “cysts” on the ovaries, PCOS is a complex whole-body condition that impacts everything from metabolism to fertility.
At its core, PCOS is characterized by a combination of three key features:
Irregular or absent menstrual cycles
Elevated levels of “male hormones” (androgens)
The presence of multiple small, fluid-filled follicles on the ovaries (detected via ultrasound)
The symptoms of PCOS can vary significantly from one woman to another, which is why it often goes undiagnosed. Common signs include:
Irregular Periods: Infrequent, prolonged, or unpredictable menstrual cycles are a hallmark sign.
Excess Androgen: This can manifest as hirsutism (excessive hair growth on the face, chest, or back), severe acne, or male-pattern baldness.
Polycystic Ovaries: The ovaries may become enlarged and contain numerous small follicles that surround the eggs.
Weight Gain and Difficulty Losing Weight: Many women with PCOS struggle with obesity and find it challenging to manage their weight.
Fertility Challenges: Irregular ovulation is a leading cause of infertility in women with PCOS.
Skin Changes: Darkening of the skin in body creases (like the neck, groin, and under the breasts), known as acanthosis nigricans, can occur.
Mood Changes: Higher rates of anxiety and depression are common.
Sleep Problems: Sleep apnea is more frequent in women with PCOS.
The exact cause of PCOS remains unknown, but research points to several key factors:
Insulin Resistance: This is a central player. When the body’s cells don’t respond well to insulin, the pancreas produces more of it. High insulin levels, in turn, boost androgen production, which disrupts ovulation.
Hormonal Imbalance: Women with PCOS often have higher levels of luteinizing hormone (LH) and androgens (like testosterone), and lower levels of sex hormone-binding globulin (SHBG).
Genetics: PCOS often runs in families, suggesting a strong genetic link.
While there is no cure for PCOS, its symptoms can be effectively managed through a combination of lifestyle changes and medical treatments. The goal is to address specific concerns and reduce long-term health risks.
Diet: A balanced diet rich in fiber, lean protein, and anti-inflammatory foods can help manage insulin resistance. Reducing sugar and refined carbohydrates is often beneficial.
Exercise: Regular physical activity helps lower blood sugar levels and can aid in weight management.
Weight Management: Losing even 5-10% of body weight can significantly improve symptoms and restart ovulation.
Hormonal Birth Control: Pills, patches, or rings can regulate menstrual cycles, reduce androgen levels, and clear acne.
Insulin-Sensitizing Medications: Drugs like Metformin are commonly used to improve the body’s response to insulin, which can help with ovulation and metabolic issues.
Fertility Treatments: For women trying to conceive, medications like Clomiphene or Letrozole can induce ovulation.
Addressing PCOS early is crucial. Effective management not only alleviates immediate symptoms but also significantly reduces the risk of developing serious long-term health complications, including Type 2 Diabetes, High Blood Pressure, Heart Disease, and Endometrial Cancer.
By taking a proactive approach through lifestyle and medical care, women with PCOS can successfully manage their symptoms and lead full, healthy lives. If you suspect you have PCOS, consulting with an endocrinologist or a gynecologist is the essential first step.
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