Shingles, also known as herpes zoster, is a viral infection caused by the reactivation of the varicella-zoster virus, which also causes chickenpox. Shingles is characterized by a painful rash that typically appears on one side of the body or face. A shingles injection, or vaccine, can help prevent the occurrence of shingles and its complications.
Mechanism
The shingles vaccine works by boosting the immune system’s ability to combat the varicella-zoster virus. By enhancing the body’s immune response, the vaccine reduces the risk of developing shingles and helps prevent complications such as postherpetic neuralgia (PHN), a condition that causes persistent pain even after the rash has healed.
Types of Shingles Vaccines
Zostavax: This live attenuated vaccine was used to reduce the risk of shingles and its complications. It has been largely replaced by the newer Shingrix vaccine.
Shingrix: This recombinant, adjuvanted vaccine is currently recommended for preventing shingles. It is administered in two doses, with the second dose given 2 to 6 months after the first.
Administration
The Shingrix vaccine is administered as an intramuscular injection, typically in the upper arm. The two doses are spaced several months apart to ensure optimal immune response.
Benefits
Prevention of Shingles: The vaccine significantly reduces the risk of developing shingles and its associated pain.
Reduction in Postherpetic Neuralgia: The vaccine lowers the risk of developing PHN, a common and debilitating complication of shingles.
Long-lasting Protection: The vaccine provides long-term protection, reducing the likelihood of shingles for several years.
Risks and Side Effects
Common Side Effects: These may include soreness at the injection site, mild fever, or fatigue. These side effects are usually short-lived.
Rare Side Effects: Severe allergic reactions are rare but can occur. Patients should be monitored for any signs of an allergic reaction following vaccination.
Eligibility
The shingles vaccine is recommended for adults aged 50 and older, regardless of whether they have had shingles previously. Vaccination is especially important for those who have not had shingles or who wish to reduce their risk of recurrent episodes.
Dr. Mohammad Hossein Delshad is a distinguished Anesthesiologist and Pain Specialist in Iran, recognized for his extensive expertise and commitment to the field […]
