Shiraz Fertility Clinic

The Shiraz Fertility Center, established in 1993, is a leading institution in Shiraz, Iran, dedicated to providing comprehensive infertility treatment services. With over 30 years of experience, the center has gained a reputation for its remarkable successes and commitment to helping couples achieve their dream of parenthood.

Overview of Shiraz Fertility Center

History and Mission

The Shiraz Fertility Center began its operations in Fars Province and has since expanded its services to cater to the southern region of Iran. The center’s mission is to ensure the birth of healthy, disorder-free children, bringing joy to families. This goal is supported by the integration of advanced medical genetics laboratories and cutting-edge technologies.

Facilities and Technology

The center is equipped with state-of-the-art medical equipment and employs the latest techniques in assisted reproductive technology (ART). This commitment to modernization allows the Shiraz Fertility Center to provide high-quality care that meets international standards.

Services Offered

Shiraz Fertility Center provides a wide range of services, including:

In Vitro Fertilization (IVF): A widely used method for assisting couples with infertility.
Intracytoplasmic Sperm Injection (ICSI): A specialized IVF technique where a single sperm is injected directly into an egg.
Egg and Sperm Donation: Assistance for couples who may require donor gametes.
Laparoscopic Surgeries: Minimally invasive surgical procedures for various reproductive issues.
Genetic Testing Services: Including preimplantation genetic diagnosis (PGD) to screen embryos for genetic conditions.
Fertility Preservation: Options for individuals looking to preserve their fertility for future use.

Expert Team

The center boasts a team of highly skilled professionals, including specialists in obstetrics and gynecology, embryology, and genetics. Under the leadership of Dr. Cyrus Rostami, the center has successfully treated thousands of patients, contributing significantly to advancements in fertility treatments within Iran.

Success Rates

The Shiraz Fertility Center reports success rates that are competitive with international standards. The overall success rate for IVF varies based on several factors, including the age of the woman and specific treatment protocols. For instance:

Women under 35 have a success rate of approximately 32%.
Women aged 35-37 have around a 25% success rate.
Rates decrease with age, with women over 44 having about a 4% chance.

International Patient Care

The Shiraz Fertility Center is committed to serving both domestic and international patients. It offers assistance with travel arrangements, accommodations, and translation services to ensure that foreign patients receive comprehensive support throughout their treatment journey.

Location and Contact Information

The Shiraz Fertility Center is located within the Ghadir Mother and Child Hospital in Gloshan Town, Shiraz. The facility is designed to provide a comfortable environment for patients undergoing treatment.Address: Ghadir Mother and Child Hospital, Gloshan Town, Shiraz, Iran
Phone: +987132279701

Conclusion

The Shiraz Fertility Center stands out as a premier destination for infertility treatment in Iran. Its dedication to employing advanced medical techniques alongside a compassionate approach to patient care makes it a trusted choice for couples seeking assistance with fertility challenges. With its experienced team and commitment to achieving successful outcomes, the center continues to fulfill its mission of bringing hope and joy to families.

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1. What is fertilization in the context of assisted reproductive technology?

Fertilization is the process where a sperm cell merges with an egg cell, resulting in the formation of a zygote. In assisted reproductive technology (ART), fertilization typically occurs in a laboratory setting during procedures like in vitro fertilization (IVF). After egg retrieval, sperm is introduced to the eggs, and successful fertilization is confirmed by the presence of two pronuclei, indicating genetic material from both parents.

2. What does embryo culture involve?

Embryo culture begins immediately after fertilization and lasts for several days. During this period, the fertilized egg, now called a zygote, is monitored as it divides and develops into an embryo. The environment for embryo culture is carefully controlled to optimize conditions for growth. Typically, embryos are cultured for two to five days before transfer to the uterus, allowing embryologists to assess their development and select the healthiest embryos for implantation.

3. How do immunological factors contribute to non-implantation and recurrent miscarriage?

Immunological factors can play a significant role in non-implantation and recurrent miscarriage of unknown origin. The immune system may mistakenly identify embryos as foreign bodies and mount an attack against them. Conditions such as antiphospholipid syndrome or elevated natural killer cell activity can interfere with implantation and lead to pregnancy loss. A thorough evaluation by a fertility specialist can help identify these issues and guide appropriate treatment.

4. What are common causes of infertility in men?

Infertility in men can be attributed to various factors, including hormonal imbalances, anatomical issues (such as varicocele), low sperm production, poor sperm motility or morphology, genetic abnormalities, and lifestyle factors like smoking or excessive alcohol consumption. A comprehensive semen analysis is often conducted to evaluate sperm health and identify potential issues.

5. What causes infertility in women?

Infertility in women can arise from several conditions, including ovulatory disorders (such as polycystic ovary syndrome), blocked fallopian tubes (often due to pelvic inflammatory disease), endometriosis, uterine abnormalities (like fibroids), and age-related factors that affect egg quality and quantity. A thorough evaluation involving hormonal tests, imaging studies, and possibly laparoscopy may be necessary to determine the underlying cause.

6. How does polycystic ovary syndrome (PCOS) affect assisted reproductive technology (ART)?

PCOS is a common hormonal disorder that can lead to infertility due to irregular ovulation. While PCOS presents challenges for conception, ART methods such as IVF can significantly enhance pregnancy chances for women with this condition. Specialized protocols may be employed to manage ovarian stimulation carefully, minimizing risks such as ovarian hyperstimulation syndrome while optimizing outcomes.

7. What is a surrogate uterus?

A surrogate uterus refers to a woman who carries and delivers a baby for another individual or couple who cannot conceive or carry a pregnancy themselves. Surrogacy can be gestational (where the surrogate has no genetic link to the child) or traditional (where the surrogate's egg is used). Legal agreements and medical evaluations are essential components of the surrogacy process.

8. What are sperm chromosomal breakage tests like TUNEL and SCSA?

Sperm chromosomal breakage tests such as TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labeling) and SCSA (Sperm Chromatin Structure Assay) are used to assess sperm DNA integrity. These tests help identify chromosomal abnormalities that may affect fertility or increase risks of miscarriage or genetic disorders in offspring.

9. What is non-invasive prenatal testing (NIPT)?

Non-invasive prenatal testing (NIPT) is a screening method that analyzes small fragments of fetal DNA circulating in a pregnant woman's blood. It provides information about the risk of certain genetic conditions, such as Down syndrome, without posing any risk to the fetus. NIPT is typically performed after ten weeks of gestation and has high accuracy rates.

10. What is blastomere biopsy?

Blastomere biopsy involves removing one or two cells from an embryo at the six-to-eight-cell stage during IVF for genetic testing purposes. This procedure allows for preimplantation genetic diagnosis (PGD) or screening (PGS) to identify genetic abnormalities before transferring the embryo into the uterus.

11. What are sex-linked genetic diseases?

Sex-linked genetic diseases are conditions caused by mutations in genes located on sex chromosomes (X or Y). X-linked diseases, which primarily affect males due to their single X chromosome, include conditions like hemophilia and Duchenne muscular dystrophy. Genetic counseling may be recommended for families with a history of these disorders.

12. What are single gene diseases?

Single gene diseases result from mutations in a single gene and can be inherited in various patterns such as autosomal dominant, autosomal recessive, or X-linked inheritance. Examples include cystic fibrosis and sickle cell anemia. Genetic testing can help identify carriers of these conditions and inform family planning decisions.

13. How are causes of recurrent miscarriage investigated?

The investigation of recurrent miscarriage typically involves a comprehensive evaluation that may include blood tests for hormonal levels, autoimmune conditions, genetic testing for both partners, ultrasound imaging to assess uterine structure, and possible karyotyping of products of conception from previous losses.

14. What is oocyte retrieval?

Oocyte retrieval is a procedure performed during IVF where mature eggs are collected from a woman's ovaries using a thin needle guided by ultrasound imaging. This minimally invasive procedure usually occurs under sedation or anesthesia and is crucial for fertilization in an IVF cycle.

15. How does immunology affect infertility in men?

Immunological factors can contribute to male infertility through mechanisms such as antisperm antibodies that attack sperm cells or autoimmune responses that impair sperm production or function. Evaluating these factors may involve blood tests or specialized semen analyses to assess immune responses affecting fertility.

16. What is oocyte donation?

Oocyte donation involves using eggs from a donor instead of the intended mother's eggs during IVF treatment. This option is often pursued by women with diminished ovarian reserve or those who cannot produce viable eggs due to age or medical conditions. Donors undergo thorough screening processes to ensure egg quality and minimize risks.

17. What are PGD indications?

Preimplantation genetic diagnosis (PGD) is indicated for couples at risk of passing on inherited genetic disorders, including those with recurrent miscarriages, advanced maternal age, prior chromosomal abnormalities in children, or specific single-gene disorders within their family history.

18. What does freezing entail in fertility treatments?

Freezing refers to cryopreservation techniques used to preserve eggs, embryos, or sperm for future use in fertility treatments. This process allows individuals or couples facing medical treatments that may affect fertility—such as cancer therapy—to retain their reproductive options later on.

19. What happens during embryo transfer?

Embryo transfer is the final step in an IVF cycle where one or more healthy embryos are placed into the woman's uterus using a thin catheter after culturing them for several days post-fertilization. The procedure is relatively simple and painless but requires careful timing based on embryo development stages.

20. How is semen evaluated in fertility assessments?

Semen evaluation involves analyzing various parameters of a man's semen sample including sperm count, motility (movement), morphology (shape), volume of ejaculate, pH level, and presence of any abnormalities such as infections or inflammation that could impact fertility potential.